Butyrylcholinesterase (BChE)
Catalogue Number: 135-10
Description
Product Name | Butyrylcholinesterase |
Source | Human Serum |
Catalogue Number | 135-10 |
Purity | Highly Purified |
Form | Lyophilized |
Activity | Reported in units/vial (Siemens Dimension® Clinical Chemistry System) |
Unit Definition | One unit will catalyze the hydrolysis of one micromole of butyrylthiocholine to thiocholine and butyrate per minute at 37°C. |
Protein | Reported in mg protein/vial (A280, E0.1%=1.6) |
Specific Activity | > 100 U/mg protein |
Appearance | White to off-white powder |
Reconstitution | Use of a phosphate buffer, pH >7.0, containing 0.15 M sodium chloride is recommended. |
Formulation | Lyophilized from 0.02 M ammonium bicarbonate. |
Related Products | 135-10 – Butyrylcholinesterase from human serum 343-10 – Esterase from porcine liver |
Storage | 2-8°C |
Recertification | 4 years |
CAS Number | 9001-08-5 |
E.C. Number | 3.1.1.8 |
Protein Form | Tetrameric glycoprotein |
Synonyms | BCHE, BuChE, PCHE, pseudocholinesterase, plasma cholinesterase, Acylcholine acylhydrolase, Butyrylcholine esterase, Choline esterase II |
Gene | BCHE, CHE1, CHE2, E1 |
Gene ID | 590 |
Accession No | P06276 |
Reaction | An acylcholine + H2O = choline + a carboxylate |
References | C. M. González Tanarro & M. Gütschow (2010) Hyperbolic mixed-type inhibition of acetylcholinesterase by tetracyclic thienopyrimidines, Journal of Enzyme Inhibition and Medicinal Chemistry, 26:3, 350-358. |